Post-grad positions available.
The Reilly Lab in the Genetics Department at Yale School of Medicine (www.reilly-lab.com) is seeking postgraduate researchers. We’re a collaborative, hard-working, and supportive team that studies (mostly) human evolutionary genomics by developing cutting-edge experimental techniques to interrogate the function of non-coding genetic variation in the human genome.
The promise of unlocking the human genome’s full potential to cure disease or understand our evolutionary history hinges on our ability to build new tools for interpreting uncharacterized genomic regions. To that end we’ve developed CRISPR editing, high-throughput reporter assays, and machine learning methods. Our lab applies these tools to understand the precise genetic mechanisms underlying complex traits, evolutionarily significant genomic loci, and disease risk for neurological, autoimmune and metabolic disorders. We are looking for strong candidates with either a human and cross-species evolutionary genomics focus, or interest in technology development in the human genetics space.
TRAINING GOALS
The Postgraduate Associate will train in developing and deploying genomic techniques such as MPRA and CRISPR screens. They will be expected to learn advanced cell culture, cloning, and next-generation sequencing techniques. The Postgraduate Associate is expected to develop into an integral, valued member of the lab, participating in weekly lab meetings/journal clubs, presenting their research findings, and attending research seminars. There is some flexibility to match the trainee’s interests and aptitude to specific computational or benchwork-based projects of interest.
MENTORING PLAN
The Reilly lab takes seriously its role in training future scientists and sees the postgraduate’s future success as the lab’s success. The Postgraduate Associate will meet regularly with the PI to discuss scientific progress and career development. Previous trainees have gone onto top-tier graduate programs, medical schools, and industry positions. Each has graduated from the lab with authorship on at least one manuscript. As a part of the Department of Genetics at the Yale School of Medicine, the lab offers an outstanding and fully resourced training environment affording the flexibility to meet the trainee’s professional goals.
EDUCATION/EXPERTISE REQUIREMENTS
For wet-lab candidates, 1+ prior molecular biology research experience is required. For computational candidates, excellent coding skills and coursework in molecular biology/genetics are required. The candidate should display a high level of initiative, logic, and creative problem-solving skills, as well as a bachelor’s degree with a solid foundation in science. The candidate is also required to have excellent personal initiative and should be excited by the prospect of working in a dynamic team. They should demonstrate previous time management skills in coordinating multiple, concurrent assignments in a multi-faceted project. Candidates should possess strong communication and computer skills, with the ability to develop technical documents and presentations.
Candidates with any experience in sequencing, coding, or mammalian cell culture are especially encouraged to apply. The appointment will be for 1-2 years, with a longer term commitment preferable. Interested candidates should e-mail their applications to steven.k.reilly@yale.edu. The application should include: (1) CV; (2) a cover letter including a brief description of research interests and how they align with the lab; and (3) contact information for 2-3 referees.
