Our holiday card contains many puns and references. Can you spot them all?

Pictured here is Dr. Thanh Thanh Nguyen utilizing CRISPR “scissors“ to make a genomic edit…

A pair of “humanized mice“.

Electroporation, a fast and efficient way to introduce DNA into living cells. Zap!

The Reilly lab is a member of the Zoonomia Consortium!

The results of a maybe too successful transfection of a GFP-expression construct.

An invaluable member of the team : the Espresso machine.

Left is the “scientist of the month“ trophy (built mostly of old lab supplies) and first introduced by lab alum Ava Mackay-Smith. Right is the prestigious Yale Genetics Retreat Entertainment Bulldog : awarded to trivia winner Catherine McGuinness!

KRAB-dCas9 : a technique that tethers a KRAB repressive domain to a Cas9 protein to perform targeted genomic silencing. Here represented as a CRAB holding a pair of (presumably dull) scissors.

Cloning Handsome Dan, Yale’s mascot!

Archaic hominid introgression is an active area of research in the lab. Pictured here, some of our distant cousins.

Thanh Thanh’s

avocado tree.

Cramming a ‘library‘ of genetic elements into our cells for an MPRA or CRISPR screen

If you didn’t get a card this year, sign up to receive it in 2024!